Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS033776-03
Application #
2272764
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1994-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Smith, George M; Strunz, Celia (2005) Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes. Glia 52:209-18
Szebenyi, Gyorgyi; Smith, George M; Li, Ping et al. (2002) Overexpression of neurofilament H disrupts normal cell structure and function. J Neurosci Res 68:185-98
Rabchevsky, A G; Smith, G M (2001) Therapeutic interventions following mammalian spinal cord injury. Arch Neurol 58:721-6
Romero, M I; Rangappa, N; Garry, M G et al. (2001) Functional regeneration of chronically injured sensory afferents into adult spinal cord after neurotrophin gene therapy. J Neurosci 21:8408-16
Romero, M I; Rangappa, N; Li, L et al. (2000) Extensive sprouting of sensory afferents and hyperalgesia induced by conditional expression of nerve growth factor in the adult spinal cord. J Neurosci 20:4435-45
Romero, M I; Romero, M A; Smith, G M (1999) Visualization of axonally transported horseradish peroxidase using enhanced immunocytochemical detection: a direct comparison with the tetramethylbenzidine method. J Histochem Cytochem 47:265-72
Romero, M I; Smith, G M (1998) Adenoviral gene transfer into the normal and injured spinal cord: enhanced transgene stability by combined administration of temperature-sensitive virus and transient immune blockade. Gene Ther 5:1612-21
Smith, G M; Hale, J H (1997) Macrophage/Microglia regulation of astrocytic tenascin: synergistic action of transforming growth factor-beta and basic fibroblast growth factor. J Neurosci 17:9624-33
Smith, G M; Hale, J; Pasnikowski, E M et al. (1996) Astrocytes infected with replication-defective adenovirus containing a secreted form of CNTF or NT3 show enhanced support of neuronal populations in vitro. Exp Neurol 139:156-66