Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29NS036296-04
Application #
6187436
Study Section
Physiology Study Section (PHY)
Program Officer
Chiu, Arlene Y
Project Start
1997-04-01
Project End
2002-03-31
Budget Start
2000-04-01
Budget End
2001-03-31
Support Year
4
Fiscal Year
2000
Total Cost
$104,657
Indirect Cost
Name
University of California Davis
Department
Physiology
Type
Schools of Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Trattnig, Sarah M; Gasiorek, Agnes; Deeb, Tarek Z et al. (2016) Copper and protons directly activate the zinc-activated channel. Biochem Pharmacol 103:109-17
Kaila, Kai; Price, Theodore J; Payne, John A et al. (2014) Cation-chloride cotransporters in neuronal development, plasticity and disease. Nat Rev Neurosci 15:637-54
Antrobus, Shane P; Lytle, Christian; Payne, John A (2012) K+-Cl- cotransporter-2 KCC2 in chicken cardiomyocytes. Am J Physiol Cell Physiol 303:C1180-91
Deeb, Tarek Z; Maguire, Jamie; Moss, Stephen J (2012) Possible alterations in GABAA receptor signaling that underlie benzodiazepine-resistant seizures. Epilepsia 53 Suppl 9:79-88
Saliba, Richard S; Kretschmannova, Karla; Moss, Stephen J (2012) Activity-dependent phosphorylation of GABAA receptors regulates receptor insertion and tonic current. EMBO J 31:2937-51
Deeb, Tarek Z; Lee, Henry H C; Walker, Joshua A et al. (2011) Hyperpolarizing GABAergic transmission depends on KCC2 function and membrane potential. Channels (Austin) 5:475-81
Lee, Henry H C; Deeb, Tarek Z; Walker, Joshua A et al. (2011) NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents. Nat Neurosci 14:736-43
Lee, Henry H C; Jurd, Rachel; Moss, Stephen J (2010) Tyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2. Mol Cell Neurosci 45:173-9