Elderly persons who have suffered a disabling medical event, such as a hip fracture, are likely to develop depression. Late-life depression (LLD) adversely affects acute medical rehabilitation, increasing the risk for persistent depression and disability. Existing acute medical rehabilitation settings ? skilled nursing facilities (SNFs) and inpatient rehabilitation facilities (IRFs) ? do not adequately meet the needs of depressed elders, resulting in a missed opportunity for affective and functional recovery. This R34 will develop enhanced medical rehabilitation for depressed older adults who are admitted to a SNF after a disabling medical event. The goal of this enhanced rehabilitative care is to reduce depressive symptoms and improve function. The intervention will consist of (1) high intensity PT &OT, and (2) comprehensive team-based management that incorporates mental health expertise. In this R34 we will develop enhanced medical rehabilitation in three stages: (1) develop a treatment manual;(2) pilot and iteratively modify the intervention;(3) carry out a preliminary randomized trial of the intervention in a SNF, with usual care comparison. The R34 is led by a multidisciplinary team with expertise in rehabilitation research and in mental health interventions in medical settings

Public Health Relevance

Disabling medical events (such as hip fracture) occur approximately 6 million times per year in elderly persons in the US. There is a high incidence of late-life depression (LLD) in this context, which interferes with recovery from the medical event and increases functional dependence, institutionalization, and mortality. If successful, this proposal will have a significant public health impact, in that it will develop an effective nonpharmacological treatment for LLD that is applicable to the acute medical rehabilitation setting.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Planning Grant (R34)
Project #
1R34MH083868-01A1
Application #
7661198
Study Section
Mental Health Services in Non-Specialty Settings (SRNS)
Program Officer
Niederehe, George T
Project Start
2009-08-20
Project End
2011-07-31
Budget Start
2009-08-20
Budget End
2010-07-31
Support Year
1
Fiscal Year
2009
Total Cost
$342,000
Indirect Cost
Name
Washington University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
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Lenze, Eric J; Host, Helen H; Hildebrand, Mary et al. (2013) Enhanced medical rehabilitation is feasible in a skilled nursing facility: preliminary data on a novel treatment for older adults with depression. Am J Geriatr Psychiatry 21:307
Lenze, Eric J; Host, Helen H; Hildebrand, Mary W et al. (2012) Enhanced medical rehabilitation increases therapy intensity and engagement and improves functional outcomes in postacute rehabilitation of older adults: a randomized-controlled trial. J Am Med Dir Assoc 13:708-12
Hildebrand, Mary W; Host, Helen H; Binder, Ellen F et al. (2012) Measuring treatment fidelity in a rehabilitation intervention study. Am J Phys Med Rehabil 91:715-24
Lenze, Eric J; Host, Helen H; Hildebrand, Mary et al. (2011) Enhanced Medical Rehabilitation Is Feasible in a Skilled Nursing Facility: Preliminary Data on a Novel Treatment for Older Adults With Depression. Am J Geriatr Psychiatry :