Abstract

Young children of mothers with Attention-Deficit/Hyperactivity Disorder (ADHD) are at heightened risk for ADHD by virtue of genetics and family environment. Maternal ADHD is associated with maladaptive parenting and a diminished response to evidence-based behavioral parent training interventions. Many questions remain with regard to how best to treat families in which the mother has ADHD and child is at risk. In this R34 application, we propose a Sequential Multiple Assessment Randomized Trial (SMART) pilot, to demonstrate feasibility, develop recruitment, assessment, treatment protocols, and test the concept of treating mothers first using either stimulant medication or behavioral parent training, and then adapting treatment based upon response in preparation for the R01 application.

Public Health Relevance

This is a pilot study to demonstrate feasibility, develop recruitment, assessment, treatment protocols, and test the concept of treating mothers with ADHD using stimulant medication or parent training, in order to improve parenting and to ultimately improve developmental outcomes for the at-risk child.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Planning Grant (R34)
Project #
1R34MH099208-01A1
Application #
8582473
Study Section
Interventions Committee for Disorders Involving Children and Their Families (ITVC)
Program Officer
Sherrill, Joel
Project Start
2013-09-01
Project End
2016-06-30
Budget Start
2013-09-01
Budget End
2014-06-30
Support Year
1
Fiscal Year
2013
Total Cost
$277,537
Indirect Cost
$91,050

  Institution

Name
Seattle Children's Hospital
Department
Type
DUNS #
048682157
City
Seattle
State
WA
Country
United States
Zip Code
98105

  Publications

Johnston, Charlotte; Chronis-Tuscano, Andrea (2017) Parental ADHD: Relations to Parenting, Child Behavior, and Treatment Outcomes. J Abnorm Child Psychol 45:411-413
Chronis-Tuscano, Andrea; Wang, Christine H; Woods, Kelsey E et al. (2017) Parent ADHD and Evidence-Based Treatment for Their Children: Review and Directions for Future Research. J Abnorm Child Psychol 45:501-517
Almirall, Daniel; Chronis-Tuscano, Andrea (2016) Adaptive Interventions in Child and Adolescent Mental Health. J Clin Child Adolesc Psychol 45:383-95
Chronis-Tuscano, Andrea; Wang, Christine H; Strickland, Jennifer et al. (2016) Personalized Treatment of Mothers With ADHD and Their Young At-Risk Children: A SMART Pilot. J Clin Child Adolesc Psychol 45:510-21
Stein, Mark A; Shaffer, Michele; Echo-Hawk, Abigail et al. (2015) Research START: A Multimethod Study of Barriers and Accelerators of Recruiting Research Participants. Clin Transl Sci 8:647-54
Wang, Christine H; Mazursky-Horowitz, Heather; Chronis-Tuscano, Andrea (2014) Delivering evidence-based treatments for child attention-deficit/hyperactivity disorder (ADHD) in the context of parental ADHD. Curr Psychiatry Rep 16:474