Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Unknown (R35)
Project #
5R35CA049734-07
Application #
2093413
Study Section
Special Emphasis Panel (SRC (88))
Project Start
1989-09-08
Project End
1997-12-31
Budget Start
1995-09-01
Budget End
1997-12-31
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Stanford University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Michie, S A; Sytwu, H K; McDevitt, J O et al. (1998) The roles of alpha 4-integrins in the development of insulin-dependent diabetes mellitus. Curr Top Microbiol Immunol 231:65-83
Yang, X D; Sytwu, H K; McDevitt, H O et al. (1997) Involvement of beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in obese diabetic mice. Diabetes 46:1542-7
Sytwu, H K; Liblau, R S; McDevitt, H O (1996) The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity 5:17-30
Fugger, L; Rothbard, J B; Sonderstrup-McDevitt, G (1996) Specificity of an HLA-DRB1*0401-restricted T cell response to type II collagen. Eur J Immunol 26:928-33
McDermott, M; Kastner, D L; Holloman, J D et al. (1995) The role of T cell receptor beta chain genes in susceptibility to rheumatoid arthritis. Arthritis Rheum 38:91-5
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Tisch, R; Yang, X D; Liblau, R S et al. (1994) Administering glutamic acid decarboxylase to NOD mice prevents diabetes. J Autoimmun 7:845-50
Yang, X D; Tisch, R; Singer, S M et al. (1994) Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J Exp Med 180:995-1004
Fugger, L; Michie, S A; Rulifson, I et al. (1994) Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response. Proc Natl Acad Sci U S A 91:6151-5
Yang, X D; Michie, S A; Tisch, R et al. (1994) Cell adhesion molecules: a selective therapeutic target for alleviation of IDDM. J Autoimmun 7:859-64

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