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Sirotnak, Francis M (2003) Studies with ZD1839 in preclinical models. Semin Oncol 30:12-20
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She, Yuhong; Lee, Fei; Chen, Jing et al. (2003) The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 selectively potentiates radiation response of human tumors in nude mice, with a marked improvement in therapeutic index. Clin Cancer Res 9:3773-8
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Sirotnak, Francis M; She, Yohung; Lee, Fei et al. (2002) Studies with CWR22 xenografts in nude mice suggest that ZD1839 may have a role in the treatment of both androgen-dependent and androgen-independent human prostate cancer. Clin Cancer Res 8:3870-6
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Masumoto, Naoko; Chen, Jing; Sirotnak, F M (2002) Regulation of transcription of the murine gamma-glutamyl hydrolase gene. Delineation of core promoter A and the role of LYF-1, E2F and ETS-1 in determining tumor-specific expression. Gene 291:169-76
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Masumoto, N; Esaki, T; Sirotnak, F M (2001) Additional organizational features of the murine gamma-glutamyl hydrolase gene. Two remotely situated exons within the complement C3 gene locus encode an alternate 5' end and proximal ORF under the control of a bidirectional promoter. Gene 268:183-94
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Sirotnak, F M; Sepp-Lorenzino, L; Kohl, N E et al. (2000) A peptidomimetic inhibitor of ras functionality markedly suppresses growth of human prostate tumor xenografts in mice. Prospects for long-term clinical utility. Cancer Chemother Pharmacol 46:79-83
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