Acquisition of a helium recovery system for Nuclear Magnetic Resonance (NMR) and Ion Cyclotron Resonance Mass (ICR-MS) Spectrometers The R35 research program Chemical Synthesis of Complex Natural Products for Translation Science (R35GM118173) is focused on the chemical synthesis of important classes of bioactive molecules and their application in translational collaborations. A supplement to purchase a helium recovery system for two NMRs and one ICR-MS will greatly reduce the purchase of liquid helium which as PA-18-591 demonstrated will become increasingly more costly and more difficult to have adequate supplies beginning in 2020. The 400 and 500 MHz NMR systems and the FT-ICR liquid chromatography mass spectrometer not only are critical to the success of the R35GM118173 MIRA program but are also routine and key characterization techniques for six other NIGMS funded groups at BU (Elliott, Grinstaff, Reinhard, Schaus, Vegas, and Whitty). A helium recovery system is requested from Quantum Design, Inc. ($249,550) to provide a closed loop system where helium is captured, re-liquefied and refilled to each of the cyro magnets. The requested instrument will fill a critical helium recovery need in the Chemical Instrumentation Center (CIC) and the Department of Chemistry where those magnets are sited.

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Acquisition of a helium recovery system for Nuclear Magnetic Resonance (NMR) and Ion Cyclotron Resonance Mass (ICR-MS) Spectrometers An administrative supplement for an Advanced Technology Liquefier and Medium Pressure Helium Recovery System is requested in response to (PA-18-591) to use in conjunction with NMR and ICR-MS spectrometers and serve and optimize the project?s liquid helium needs. The Advanced Technology Liquefier (ATL) - Medium Pressure Helium Recovery system will be used to recover the helium boil off from three heavily used spectrometer magnets. The increasing shortage of liquid helium is resulting in both infrequent supplies and regular price hikes. The ATL-Helium recovery system will help reduce the project?s dependency on commercial liquid helium and will also ensure the stability of the project?s future cryogenic needs.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Unknown (R35)
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Special Emphasis Panel (ZGM1)
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Bond, Michelle Rueffer
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Boston University
Schools of Arts and Sciences
United States
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