Stereochemically defined organic molecules play a crucial role in drug development and advances in medicine. Catalytic, efficient, selective, broadly applicable, practical (scalable) methods that provide access to such entities, and that are sustainable and cost effective (e.g., no precious metals) are much needed and in great demand. Despite notable recent advances, existing methods for the preparation of important bioactive compounds often do not satisfy many of the above criteria. The principal goal of this program is to design catalysts, and develop methods that address the above issues.

Public Health Relevance

Catalysts provide access to otherwise inaccessible compounds, and do so with minimal energy expenditure and waste generation. We will develop new catalysts and methods for preparation of bioactive molecules with maximum efficiency and minimal cost.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Unknown (R35)
Project #
5R35GM130395-02
Application #
9841943
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Yang, Jiong
Project Start
2019-01-01
Project End
2023-12-31
Budget Start
2020-01-01
Budget End
2020-12-31
Support Year
2
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Boston College
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
045896339
City
Chestnut Hill
State
MA
Country
United States
Zip Code
02467