Amyloidosis and Alzheimer's Disease

Frangione, Blas

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Aging (NIA)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 5R37AG005891-21
• Application #: 7090071
• Study Section: Special Emphasis Panel (NSS)
• Program Officer: Snyder, Stephen D
• Project Start: 1985-07-01
• Project End: 2009-06-30
• Budget Start: 2006-07-15
• Budget End: 2009-06-30
• Support Year: 21
• Fiscal Year: 2006
• Total Cost: $519,009

Institution

• Name: New York University
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 121911077
• City: New York
• State: NY
• Country: United States
• Zip Code: 10016

Publications

Tomidokoro, Yasushi; Rostagno, Agueda; Neubert, Thomas A et al. (2010) Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits. Am J Pathol 176:1841-54

Boutajangout, Allal; Goni, Fernando; Knudsen, Elin et al. (2009) Diminished amyloid-beta burden in Tg2576 mice following a prophylactic oral immunization with a salmonella-based amyloid-beta derivative vaccine. J Alzheimers Dis 18:961-72

Trouche, Stéphanie G; Asuni, Ayodeji; Rouland, Sylvie et al. (2009) Antibody response and plasma Abeta1-40 levels in young Microcebus murinus primates immunized with Abeta1-42 and its derivatives. Vaccine 27:957-64

Lashley, T; Revesz, T; Plant, G et al. (2008) Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease. Neuropathol Appl Neurobiol 34:492-505

Berry, Anne; Tomidokoro, Yasushi; Ghiso, Jorge et al. (2008) Human chorionic gonadotropin (a luteinizing hormone homologue) decreases spatial memory and increases brain amyloid-beta levels in female rats. Horm Behav 54:143-52