Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AG009241-10
Application #
6590051
Study Section
Special Emphasis Panel (NSS)
Program Officer
Sherman, Sherry
Project Start
1991-07-01
Project End
2008-07-31
Budget Start
2003-09-01
Budget End
2004-07-31
Support Year
10
Fiscal Year
2003
Total Cost
$324,993
Indirect Cost
Name
University of Florida
Department
Physiology
Type
Schools of Veterinary Medicine
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Downey, M E; Holliday, L S; Aguirre, J I et al. (2009) In vitro and in vivo evidence for stimulation of bone resorption by an EP4 receptor agonist and basic fibroblast growth factor: Implications for their efficacy as bone anabolic agents. Bone 44:266-74
Iwaniec, U T; Moore, K; Rivera, M F et al. (2007) A comparative study of the bone-restorative efficacy of anabolic agents in aged ovariectomized rats. Osteoporos Int 18:351-62
Aguirre, J Ignacio; Leal, Martha E; Rivera, Mercedes F et al. (2007) Effects of basic fibroblast growth factor and a prostaglandin E2 receptor subtype 4 agonist on osteoblastogenesis and adipogenesis in aged ovariectomized rats. J Bone Miner Res 22:877-88
Power, R A; Iwaniec, U T; Magee, K A et al. (2004) Basic fibroblast growth factor has rapid bone anabolic effects in ovariectomized rats. Osteoporos Int 15:716-23
Iwaniec, U T; Magee, K A; Mitova-Caneva, N G et al. (2003) Bone anabolic effects of subcutaneous treatment with basic fibroblast growth factor alone and in combination with estrogen in osteopenic ovariectomized rats. Bone 33:380-6
Pun, S; Dearden, R L; Ratkus, A M et al. (2001) Decreased bone anabolic effect of basic fibroblast growth factor at fatty marrow sites in ovariectomized rats. Bone 28:220-6
Pun, S; Florio, C L; Wronski, T J (2000) Anabolic effects of basic fibroblast growth factor in the tibial diaphysis of ovariectomized rats. Bone 27:197-202
Liang, H; Pun, S; Wronski, T J (1999) Bone anabolic effects of basic fibroblast growth factor in ovariectomized rats. Endocrinology 140:5780-8
Westerlind, K C; Wronski, T J; Ritman, E L et al. (1997) Estrogen regulates the rate of bone turnover but bone balance in ovariectomized rats is modulated by prevailing mechanical strain. Proc Natl Acad Sci U S A 94:4199-204
Miller, S C; Hunziker, J; Mecham, M et al. (1997) Intermittent parathyroid hormone administration stimulates bone formation in the mandibles of aged ovariectomized rats. J Dent Res 76:1471-6

Showing the most recent 10 out of 11 publications