Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
7R37AG023806-14
Application #
9662565
Study Section
Special Emphasis Panel (NSS)
Program Officer
Williams, John
Project Start
2015-08-01
Project End
2020-04-30
Budget Start
2018-05-01
Budget End
2019-04-30
Support Year
14
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Stanford University
Department
Neurology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94304
Liu, Ling; Charville, Gregory W; Cheung, Tom H et al. (2018) Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells. Cell Stem Cell 23:544-556.e4
Quarta, Marco; Cromie Lear, Melinda J; Blonigan, Justin et al. (2018) Biomechanics show stem cell necessity for effective treatment of volumetric muscle loss using bioengineered constructs. NPJ Regen Med 3:18
Filareto, Antonio; Maguire-Nguyen, Katie; Gan, Qiang et al. (2018) Monitoring disease activity noninvasively in the mdx model of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A 115:7741-7746
Tabula Muris Consortium; Overall coordination; Logistical coordination et al. (2018) Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris. Nature 562:367-372
Wosczyna, Michael N; Rando, Thomas A (2018) A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration. Dev Cell 46:135-143
Leeman, Dena S; Hebestreit, Katja; Ruetz, Tyson et al. (2018) Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging. Science 359:1277-1283
van Velthoven, Cindy T J; de Morree, Antoine; Egner, Ingrid M et al. (2017) Transcriptional Profiling of Quiescent Muscle Stem Cells In Vivo. Cell Rep 21:1994-2004
de Morrée, Antoine; van Velthoven, Cindy T J; Gan, Qiang et al. (2017) Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence. Proc Natl Acad Sci U S A 114:E8996-E9005
Luo, Dan; de Morree, Antoine; Boutet, Stephane et al. (2017) Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c. Proc Natl Acad Sci U S A 114:E3071-E3080
Stearns-Reider, Kristen M; D'Amore, Antonio; Beezhold, Kevin et al. (2017) Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion. Aging Cell 16:518-528

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