Continuation of combined clinical and immunologic study of hay fever is proposed. Matched groups of patients will be compared in control studies of immunotherapy with standard or improved pollen extracts. Clinical evaluation by symptom diary and challenge tests, including observation of mediator appearance in secretions during both the early and late phase response will be performed. Laboratory evaluation by basophile histamine release and IgE, and IgG antibody levels in serum and secretions will be correlated.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI004866-32
Application #
2057752
Study Section
Special Emphasis Panel (NSS)
Project Start
1976-12-01
Project End
1996-11-30
Budget Start
1993-12-01
Budget End
1994-11-30
Support Year
32
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218