Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI014102-20
Application #
2060041
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1978-09-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Seattle Biomedical Research Institute
Department
Type
DUNS #
City
Seattle
State
WA
Country
United States
Zip Code
98109
Carnes, Jason; Anupama, Atashi; Balmer, Oliver et al. (2015) Genome and phylogenetic analyses of Trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty. PLoS Negl Trop Dis 9:e3404
Carnes, Jason; Lerch, Melissa; Kurtz, Irina et al. (2015) Bloodstream form Trypanosoma brucei do not require mRPN1 for gRNA processing. RNA 21:28-35
Demir, Ozlem; Labaied, Mehdi; Merritt, Chris et al. (2014) Computer-aided discovery of Trypanosoma brucei RNA-editing terminal uridylyl transferase 2 inhibitors. Chem Biol Drug Des 84:131-9
Beck, Kirsten; Acestor, Nathalie; Schulfer, Anjelique et al. (2013) Trypanosoma brucei Tb927.2.6100 is an essential protein associated with kinetoplast DNA. Eukaryot Cell 12:970-8
Guo, Xuemin; Carnes, Jason; Ernst, Nancy Lewis et al. (2012) KREPB6, KREPB7, and KREPB8 are important for editing endonuclease function in Trypanosoma brucei. RNA 18:308-20
Carnes, Jason; Lewis Ernst, Nancy; Wickham, Carey et al. (2012) KREX2 is not essential for either procyclic or bloodstream form Trypanosoma brucei. PLoS One 7:e33405
Lerch, Melissa; Carnes, Jason; Acestor, Nathalie et al. (2012) Editosome accessory factors KREPB9 and KREPB10 in Trypanosoma brucei. Eukaryot Cell 11:832-43
Carnes, Jason; Soares, Carmen Zelaya; Wickham, Carey et al. (2011) Endonuclease associations with three distinct editosomes in Trypanosoma brucei. J Biol Chem 286:19320-30
Ernst, Nancy Lewis; Panicucci, Brian; Carnes, Jason et al. (2009) Differential functions of two editosome exoUases in Trypanosoma brucei. RNA 15:947-57
Tarun Jr, Salvador Zipagan; Schnaufer, Achim; Ernst, Nancy Lewis et al. (2008) KREPA6 is an RNA-binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA 14:347-58

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