Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI014579-18
Application #
2060084
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-02-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Viret, Christophe; He, Xin; Janeway Jr, Charles A (2003) Altered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection. Proc Natl Acad Sci U S A 100:5354-9
Viret, Christophe; Janeway Jr, Charles A (2003) Self-specific MHC class II-restricted CD4-CD8- T cells that escape deletion and lack regulatory activity. J Immunol 170:201-9
Bynoe, Margaret S; Evans, J Tori; Viret, Christophe et al. (2003) Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis. Immunity 19:317-28
He, Xin; Janeway Jr, Charles A; Levine, Matthew et al. (2002) Dual receptor T cells extend the immune repertoire for foreign antigens. Nat Immunol 3:127-34
Viret, C; Sant'Angelo, D B; He, X et al. (2001) A role for accessibility to self-peptide-self-MHC complexes in intrathymic negative selection. J Immunol 166:4429-37
Das, G; Sheridan, S; Janeway Jr, C A (2001) The source of early IFN-gamma that plays a role in Th1 priming. J Immunol 167:2004-10
Viret, C; He, X; Janeway Jr, C A (2001) Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide. Proc Natl Acad Sci U S A 98:9243-8
Viret, C; Barlow, A K; Janeway Jr, C A (2000) Polymorphism of the mouse T-cell receptor AV20S1 gene. Immunogenetics 51:392-4
Levine, M H; Haberman, A M; Sant'Angelo, D B et al. (2000) A B-cell receptor-specific selection step governs immature to mature B cell differentiation. Proc Natl Acad Sci U S A 97:2743-8
Viret, C; He, X; Janeway Jr, C A (2000) On the self-referential nature of naive MHC class II-restricted T cells. J Immunol 165:6183-92

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