Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
7R37AI014784-13
Application #
3480805
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1989-12-01
Project End
1991-04-30
Budget Start
1989-12-01
Budget End
1990-04-30
Support Year
13
Fiscal Year
1989
Total Cost
Indirect Cost
Name
La Jolla Institute
Department
Type
DUNS #
603880287
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Ishizaka, K; Ishii, Y; Nakano, T et al. (2000) Biochemical basis of antigen-specific suppressor T cell factors: controversies and possible answers. Adv Immunol 74:Jan-60
Sugie, K; Tomura, T; Takakura, K et al. (1999) Target cells for an immunosuppressive cytokine, glycosylation-inhibiting factor. Int Immunol 11:1149-56
Sugie, K; Nakano, T; Tomura, T et al. (1997) High-affinity binding of bioactive glycosylation-inhibiting factor to antigen-primed T cells and natural killer cells. Proc Natl Acad Sci U S A 94:5278-83
Nakano, T; Watarai, H; Liu, Y C et al. (1997) Conversion of inactive glycosylation inhibiting factor to bioactive derivatives by modification of a SH group. Proc Natl Acad Sci U S A 94:202-7
Nakano, T; Ishii, Y; Ishizaka, K (1996) Biochemical characterization of antigen-specific glycosylation-inhibiting factor from antigen-specific suppressor T cells. I. Identification of a 55-kilodalton glycosylation-inhibiting factor peptide with TCR alpha-chain determinant. J Immunol 156:1728-34
Ishii, Y; Nakano, T; Ishizaka, K (1996) Biochemical characterization of antigen-specific glycosylation-inhibiting factor from antigen-specific suppressor T cells. II. The 55-kDa glycosylation-inhibiting factor peptide is a derivative of TCR alpha-chain and a subunit of antigen-specific glycosyl J Immunol 156:1735-42
Ishizaka, K; Nakano, T; Ishii, Y et al. (1996) Controversial issues and possible answers on the antigen-specific regulation of the IgE antibody response. Adv Exp Med Biol 409:317-25
Nakano, T; Liu, Y C; Mikayama, T et al. (1995) Association of the ""major histocompatibility complex subregion"" I-J determinant with bioactive glycosylation-inhibiting factor. Proc Natl Acad Sci U S A 92:9196-200
Liu, Y C; Nakano, T; Elly, C et al. (1994) Requirement of posttranslational modifications for the generation of biologic activity of glycosylation-inhibiting factor. Proc Natl Acad Sci U S A 91:11227-31
Mori, A; Thomas, P; Tagaya, Y et al. (1993) Epitope specificity of bee venom phospholipase A2-specific suppressor T cells which produce antigen-binding glycosylation inhibiting factor. Int Immunol 5:833-42

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