Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI015608-17
Application #
2060250
Study Section
Special Emphasis Panel (NSS)
Project Start
1991-09-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Type
Organized Research Units
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Moser, Emily K; Sun, Jie; Kim, Taeg S et al. (2015) IL-21R signaling suppresses IL-17+ gamma delta T cell responses and production of IL-17 related cytokines in the lung at steady state and after Influenza A virus infection. PLoS One 10:e0120169
Moser, Emily K; Hufford, Matthew M; Braciale, Thomas J (2014) Late engagement of CD86 after influenza virus clearance promotes recovery in a FoxP3+ regulatory T cell dependent manner. PLoS Pathog 10:e1004315
Yoo, Jae-Kwang; Braciale, Thomas J (2014) IL-21 promotes late activator APC-mediated T follicular helper cell differentiation in experimental pulmonary virus infection. PLoS One 9:e105872
Sun, Jie; Braciale, Thomas J (2013) Role of T cell immunity in recovery from influenza virus infection. Curr Opin Virol 3:425-9
Yoo, Jae-Kwang; Fish, Eleanor N; Braciale, Thomas J (2012) LAPCs promote follicular helper T cell differentiation of Ag-primed CD4+ T cells during respiratory virus infection. J Exp Med 209:1853-67
Sun, Jie; Dodd, Haley; Moser, Emily K et al. (2011) CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs. Nat Immunol 12:327-34
Kim, Taeg S; Sun, Jie; Braciale, Thomas J (2011) T cell responses during influenza infection: getting and keeping control. Trends Immunol 32:225-31
Sun, Jie; Cardani, Amber; Sharma, Ashish K et al. (2011) Autocrine regulation of pulmonary inflammation by effector T-cell derived IL-10 during infection with respiratory syncytial virus. PLoS Pathog 7:e1002173
Yoon, Heesik; Kim, Taeg S; Braciale, Thomas J (2010) The cell cycle time of CD8+ T cells responding in vivo is controlled by the type of antigenic stimulus. PLoS One 5:e15423
Ream, Rebecca M; Sun, Jie; Braciale, Thomas J (2010) Stimulation of naive CD8+ T cells by a variant viral epitope induces activation and enhanced apoptosis. J Immunol 184:2401-9

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