Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI015940-25
Application #
6760895
Study Section
Special Emphasis Panel (ZRG1-BM-1 (06))
Program Officer
Taylor, Christopher E,
Project Start
1979-04-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
25
Fiscal Year
2004
Total Cost
$494,244
Indirect Cost
Name
University of Colorado Denver
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Oglesby-Sherrouse, Amanda G; Djapgne, Louise; Nguyen, Angela T et al. (2014) The complex interplay of iron, biofilm formation, and mucoidy affecting antimicrobial resistance of Pseudomonas aeruginosa. Pathog Dis 70:307-20
Wiens, Jacinta R; Vasil, Adriana I; Schurr, Michael J et al. (2014) Iron-regulated expression of alginate production, mucoid phenotype, and biofilm formation by Pseudomonas aeruginosa. MBio 5:e01010-13
Ibarguren, Maitane; Sot, Jesús; Montes, L Ruth et al. (2013) Recruitment of a phospholipase C/sphingomyelinase into non-lamellar lipid droplets during hydrolysis of lipid bilayers. Chem Phys Lipids 166:12-7
Truan, Daphné; Vasil, Adriana; Stonehouse, Martin et al. (2013) High-level over-expression, purification, and crystallization of a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa. Protein Expr Purif 90:40-6
Vasil, Michael L; Tomaras, Andrew P; Pritchard, Arthur E (2012) Identification and evaluation of twin-arginine translocase inhibitors. Antimicrob Agents Chemother 56:6223-34
Young, Robert L; Malcolm, Kenneth C; Kret, Jennifer E et al. (2011) Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR. PLoS One 6:e23637
Funken, Horst; Knapp, Andreas; Vasil, Michael L et al. (2011) The lipase LipA (PA2862) but not LipC (PA4813) from Pseudomonas aeruginosa influences regulation of pyoverdine production and expression of the sigma factor PvdS. J Bacteriol 193:5858-60
Oglesby-Sherrouse, Amanda G; Vasil, Michael L (2010) Characterization of a heme-regulated non-coding RNA encoded by the prrF locus of Pseudomonas aeruginosa. PLoS One 5:e9930
Jiang, Ziqing; Vasil, Adriana I; Hale, John D et al. (2008) Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. Biopolymers 90:369-83
Lucarelli, Debora; Vasil, Michael L; Meyer-Klaucke, Wolfram et al. (2008) The Metal-Dependent Regulators FurA and FurB from Mycobacterium Tuberculosis. Int J Mol Sci 9:1548-1560

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