Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI017134-17
Application #
2060457
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-12-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206
Clayton, Gina M; Wang, Yang; Crawford, Frances et al. (2014) Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell 158:132-42
Clambey, Eric T; Collins, Bernard; Young, Mary H et al. (2013) The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells. PLoS One 8:e57435
Dai, Shaodong; Murphy, Guinevere A; Crawford, Frances et al. (2010) Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc Natl Acad Sci U S A 107:7425-30
Stadinski, Brian D; Zhang, Li; Crawford, Frances et al. (2010) Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc Natl Acad Sci U S A 107:10978-83
Wang, Yibing; Becker, Dean; Vass, Tibor et al. (2009) A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. PLoS Biol 7:e1000253
Rubtsova, Kira; Scott-Browne, James P; Crawford, Frances et al. (2009) Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proc Natl Acad Sci U S A 106:7951-6
Huseby, Eric S; Crawford, Frances; White, Janice et al. (2006) Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nat Immunol 7:1191-9
Marsden, Vanessa S; Kappler, John W; Marrack, Philippa C (2006) Homeostasis of the memory T cell pool. Int Arch Allergy Immunol 139:63-74
Willis, Richard A; Kappler, John W; Marrack, Philippa C (2006) CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proc Natl Acad Sci U S A 103:12063-8
Robertson, Jennifer M; MacLeod, Megan; Marsden, Vanessa S et al. (2006) Not all CD4+ memory T cells are long lived. Immunol Rev 211:49-57

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