Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI019883-13
Application #
2061054
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1993-09-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Huang, Minzhou; Pring, Martin; Yang, Changsong et al. (2005) Presence of a novel inhibitor of capping protein in neutrophil extract. Cell Motil Cytoskeleton 62:232-43
Yang, Changsong; Pring, Martin; Wear, Martin A et al. (2005) Mammalian CARMIL inhibits actin filament capping by capping protein. Dev Cell 9:209-21
Tcheperegine, Serguei E; Gao, Xiang-Dong; Bi, Erfei (2005) Regulation of cell polarity by interactions of Msb3 and Msb4 with Cdc42 and polarisome components. Mol Cell Biol 25:8567-80
Zigmond, Sally H (2004) Formin-induced nucleation of actin filaments. Curr Opin Cell Biol 16:99-105
Pring, Martin; Evangelista, Marie; Boone, Charles et al. (2003) Mechanism of formin-induced nucleation of actin filaments. Biochemistry 42:486-96
Evangelista, Marie; Zigmond, Sally; Boone, Charles (2003) Formins: signaling effectors for assembly and polarization of actin filaments. J Cell Sci 116:2603-11
Zigmond, Sally H; Evangelista, Marie; Boone, Charles et al. (2003) Formin leaky cap allows elongation in the presence of tight capping proteins. Curr Biol 13:1820-3
Pruyne, David; Evangelista, Marie; Yang, Changsong et al. (2002) Role of formins in actin assembly: nucleation and barbed-end association. Science 297:612-5
Pring, Martin; Cassimeris, Lynne; Zigmond, Sally H (2002) An unexplained sequestration of latrunculin A is required in neutrophils for inhibition of actin polymerization. Cell Motil Cytoskeleton 52:122-30
Yang, C; Huang, M; DeBiasio, J et al. (2000) Profilin enhances Cdc42-induced nucleation of actin polymerization. J Cell Biol 150:1001-12

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