Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI020017-14
Application #
2061089
Study Section
Experimental Virology Study Section (EVR)
Project Start
1983-04-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Lin, Yi; Racaniello, Vincent R (2017) Polioviruses that bind a chimeric Pvr-nectin-2 protein identify capsid residues involved in receptor interaction. Virology 510:305-315
Kim, Melissa Stewart; Racaniello, Vincent R (2007) Enterovirus 70 receptor utilization is controlled by capsid residues that also regulate host range and cytopathogenicity. J Virol 81:8648-55
Brown, David M; Kauder, Steven E; Cornell, Christopher T et al. (2004) Cell-dependent role for the poliovirus 3' noncoding region in positive-strand RNA synthesis. J Virol 78:1344-51
Tsang, S K; McDermott, B M; Racaniello, V R et al. (2001) Kinetic analysis of the effect of poliovirus receptor on viral uncoating: the receptor as a catalyst. J Virol 75:4984-9
McDermott Jr, B M; Rux, A H; Eisenberg, R J et al. (2000) Two distinct binding affinities of poliovirus for its cellular receptor. J Biol Chem 275:23089-96
Dove, A W; Racaniello, V R (2000) An antiviral compound that blocks structural transitions of poliovirus prevents receptor binding at low temperatures. J Virol 74:3929-31
Belnap, D M; McDermott Jr, B M; Filman, D J et al. (2000) Three-dimensional structure of poliovirus receptor bound to poliovirus. Proc Natl Acad Sci U S A 97:73-8
Liao, S; Racaniello, V (1997) Allele-specific adaptation of poliovirus VP1 B-C loop variants to mutant cell receptors. J Virol 71:9770-7
Zhang, S; Racaniello, V R (1997) Persistent echovirus infection of mouse cells expressing the viral receptor VLA-2. Virology 235:293-301
Dove, A W; Racaniello, V R (1997) Cold-adapted poliovirus mutants bypass a postentry replication block. J Virol 71:4728-35

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