Antigens of Toxoplasma Gondii and Their Genes

Boothroyd, John C.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 5R37AI021423-11
• Application #: 2061516
• Study Section: Tropical Medicine and Parasitology Study Section (TMP)
• Project Start: 1985-07-01
• Project End: 1999-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 11
• Fiscal Year: 1996

Institution

• Name: Stanford University
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 800771545
• City: Stanford
• State: CA
• Country: United States
• Zip Code: 94305

Publications

Krishnamurthy, Shruthi; Deng, Bin; Del Rio, Roxana et al. (2016) Not a Simple Tether: Binding of Toxoplasma gondii AMA1 to RON2 during Invasion Protects AMA1 from Rhomboid-Mediated Cleavage and Leads to Dephosphorylation of Its Cytosolic Tail. MBio 7:

Christian, David A; Koshy, Anita A; Reuter, Morgan A et al. (2014) Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis. Infect Immun 82:4056-67

Fritz, Heather M; Buchholz, Kerry R; Chen, Xiucui et al. (2012) Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PLoS One 7:e29998

Fritz, Heather M; Bowyer, Paul W; Bogyo, Matthew et al. (2012) Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS One 7:e29955

Garrison, Erin; Treeck, Moritz; Ehret, Emma et al. (2012) A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma. PLoS Pathog 8:e1003049

Koshy, Anita A; Dietrich, Hans K; Christian, David A et al. (2012) Toxoplasma co-opts host cells it does not invade. PLoS Pathog 8:e1002825

Morgado, Pedro; Ong, Yi-Ching; Boothroyd, John C et al. (2011) Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun 79:4401-12

Treeck, Moritz; Sanders, John L; Elias, Joshua E et al. (2011) The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries. Cell Host Microbe 10:410-9

Caffaro, Carolina E; Boothroyd, John C (2011) Evidence for host cells as the major contributor of lipids in the intravacuolar network of Toxoplasma-infected cells. Eukaryot Cell 10:1095-9

Tyler, Jessica S; Treeck, Moritz; Boothroyd, John C (2011) Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication. Trends Parasitol 27:410-20