Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI021423-11
Application #
2061516
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1985-07-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Krishnamurthy, Shruthi; Deng, Bin; Del Rio, Roxana et al. (2016) Not a Simple Tether: Binding of Toxoplasma gondii AMA1 to RON2 during Invasion Protects AMA1 from Rhomboid-Mediated Cleavage and Leads to Dephosphorylation of Its Cytosolic Tail. MBio 7:
Christian, David A; Koshy, Anita A; Reuter, Morgan A et al. (2014) Use of transgenic parasites and host reporters to dissect events that promote interleukin-12 production during toxoplasmosis. Infect Immun 82:4056-67
Fritz, Heather M; Buchholz, Kerry R; Chen, Xiucui et al. (2012) Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PLoS One 7:e29998
Fritz, Heather M; Bowyer, Paul W; Bogyo, Matthew et al. (2012) Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS One 7:e29955
Garrison, Erin; Treeck, Moritz; Ehret, Emma et al. (2012) A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma. PLoS Pathog 8:e1003049
Koshy, Anita A; Dietrich, Hans K; Christian, David A et al. (2012) Toxoplasma co-opts host cells it does not invade. PLoS Pathog 8:e1002825
Tyler, Jessica S; Boothroyd, John C (2011) The C-terminus of Toxoplasma RON2 provides the crucial link between AMA1 and the host-associated invasion complex. PLoS Pathog 7:e1001282
Straub, Kurtis W; Peng, Eric D; Hajagos, Bettina E et al. (2011) The moving junction protein RON8 facilitates firm attachment and host cell invasion in Toxoplasma gondii. PLoS Pathog 7:e1002007
Morgado, Pedro; Ong, Yi-Ching; Boothroyd, John C et al. (2011) Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun 79:4401-12
Treeck, Moritz; Sanders, John L; Elias, Joshua E et al. (2011) The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries. Cell Host Microbe 10:410-9

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