Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI022125-16
Application #
6076743
Study Section
Special Emphasis Panel (NSS)
Program Officer
Deckhut Augustine, Alison M
Project Start
1985-09-30
Project End
2005-07-31
Budget Start
2000-08-01
Budget End
2001-07-31
Support Year
16
Fiscal Year
2000
Total Cost
$337,560
Indirect Cost
Name
Trudeau Institute, Inc.
Department
Type
DUNS #
City
Saranac Lake
State
NY
Country
United States
Zip Code
12983
Kamperschroer, Cris; Roberts, Deborah M; Zhang, Yongqing et al. (2008) SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation. J Immunol 181:3994-4003
Kamperschroer, Cris; Dibble, John P; Meents, Dana L et al. (2006) SAP is required for Th cell function and for immunity to influenza. J Immunol 177:5317-27
Swain, S L (2000) CD4 T-cell memory can persist in the absence of class II. Philos Trans R Soc Lond B Biol Sci 355:407-11
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Croft, M; Swain, S L (1995) Recently activated naive CD4 T cells can help resting B cells, and can produce sufficient autocrine IL-4 to drive differentiation to secretion of T helper 2-type cytokines. J Immunol 154:4269-82
Dubey, C; Croft, M; Swain, S L (1995) Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response. J Immunol 155:45-57

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