Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37AI022159-13
Application #
2061722
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1985-09-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Physiology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

McCormick, John K; Bohach, Gregory A; Schlievert, Patrick M (2003) Pyrogenic, lethal, and emetic properties of superantigens in rabbits and primates. Methods Mol Biol 214:245-53
McCormick, John K; Tripp, Timothy J; Llera, Andrea S et al. (2003) Functional analysis of the TCR binding domain of toxic shock syndrome toxin-1 predicts further diversity in MHC class II/superantigen/TCR ternary complexes. J Immunol 171:1385-92
Dinges, Martin M; Gregerson, Dale S; Tripp, Timothy J et al. (2003) Effects of total body irradiation and cyclosporin a on the lethality of toxic shock syndrome toxin-1 in a rabbit model of toxic shock syndrome. J Infect Dis 188:1142-5
Orwin, Paul M; Leung, Donald Y M; Tripp, Timothy J et al. (2002) Characterization of a novel staphylococcal enterotoxin-like superantigen, a member of the group V subfamily of pyrogenic toxins. Biochemistry 41:14033-40
Vojtov, Nikola; Ross, Hope F; Novick, Richard P (2002) Global repression of exotoxin synthesis by staphylococcal superantigens. Proc Natl Acad Sci U S A 99:10102-7
Yarwood, Jeremy M; McCormick, John K; Paustian, Michael L et al. (2002) Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3. Implications for the evolution of staphylococcal pathogenicity islands. J Biol Chem 277:13138-47
McCormick, J K; Yarwood, J M; Schlievert, P M (2001) Toxic shock syndrome and bacterial superantigens: an update. Annu Rev Microbiol 55:77-104
Yarwood, J M; McCormick, J K; Schlievert, P M (2001) Identification of a novel two-component regulatory system that acts in global regulation of virulence factors of Staphylococcus aureus. J Bacteriol 183:1113-23
Dinges, M M; Schlievert, P M (2001) Comparative analysis of lipopolysaccharide-induced tumor necrosis factor alpha activity in serum and lethality in mice and rabbits pretreated with the staphylococcal superantigen toxic shock syndrome toxin 1. Infect Immun 69:7169-72
Ruzin, A; Lindsay, J; Novick, R P (2001) Molecular genetics of SaPI1--a mobile pathogenicity island in Staphylococcus aureus. Mol Microbiol 41:365-77

Showing the most recent 10 out of 46 publications