Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI022839-09
Application #
2062005
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1985-12-01
Project End
1997-11-30
Budget Start
1993-12-01
Budget End
1994-11-30
Support Year
9
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Doherty, Timothy; Waring, Alan J; Hong, Mei (2006) Peptide-lipid interactions of the beta-hairpin antimicrobial peptide tachyplesin and its linear derivatives from solid-state NMR. Biochim Biophys Acta 1758:1285-91
Tang, Ming; Waring, Alan J; Lehrer, Robert I et al. (2006) Orientation of a beta-hairpin antimicrobial peptide in lipid bilayers from two-dimensional dipolar chemical-shift correlation NMR. Biophys J 90:3616-24
Mani, Rajeswari; Waring, Alan J; Lehrer, Robert I et al. (2005) Membrane-disruptive abilities of beta-hairpin antimicrobial peptides correlate with conformation and activity: a 31P and 1H NMR study. Biochim Biophys Acta 1716:11-8
Buffy, Jarrod J; Waring, Alan J; Hong, Mei (2005) Determination of peptide oligomerization in lipid bilayers using 19F spin diffusion NMR. J Am Chem Soc 127:4477-83
Tang, Ming; Waring, Alan J; Hong, Mei (2005) Intermolecular packing and alignment in an ordered beta-hairpin antimicrobial peptide aggregate from 2D solid-state NMR. J Am Chem Soc 127:13919-27
Buffy, Jarrod J; McCormick, Melissa J; Wi, Sungsool et al. (2004) Solid-state NMR investigation of the selective perturbation of lipid bilayers by the cyclic antimicrobial peptide RTD-1. Biochemistry 43:9800-12
Mani, Rajeswari; Buffy, Jarrod J; Waring, Alan J et al. (2004) Solid-state NMR investigation of the selective disruption of lipid membranes by protegrin-1. Biochemistry 43:13839-48
Owen, S M; Rudolph, D; Wang, W et al. (2004) A theta-defensin composed exclusively of D-amino acids is active against HIV-1. J Pept Res 63:469-76
Wang, Wei; Owen, Sherry M; Rudolph, Donna L et al. (2004) Activity of alpha- and theta-defensins against primary isolates of HIV-1. J Immunol 173:515-20
Cole, Alexander M; Lehrer, Robert I (2003) Minidefensins: antimicrobial peptides with activity against HIV-1. Curr Pharm Des 9:1463-73

Showing the most recent 10 out of 95 publications