Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI026791-18
Application #
6910843
Study Section
Special Emphasis Panel (NSS)
Program Officer
Mallia, Conrad M
Project Start
1988-07-01
Project End
2008-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
18
Fiscal Year
2005
Total Cost
$408,750
Indirect Cost
Name
Yale University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Jackman, Rachael P; Balamuth, Fran; Bottomly, Kim (2007) CTLA-4 differentially regulates the immunological synapse in CD4 T cell subsets. J Immunol 178:5543-51
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Meyer zum Bueschenfelde, Christian O; Unternaehrer, Julia; Mellman, Ira et al. (2004) Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells. J Immunol 173:6119-24
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Brogdon, Jennifer L; Leitenberg, David; Bottomly, Kim (2002) The potency of TCR signaling differentially regulates NFATc/p activity and early IL-4 transcription in naive CD4+ T cells. J Immunol 168:3825-32
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Constant, S L; Lee, K S; Bottomly, K (2000) Site of antigen delivery can influence T cell priming: pulmonary environment promotes preferential Th2-type differentiation. Eur J Immunol 30:840-7
Welte, T; Leitenberg, D; Dittel, B N et al. (1999) The PTK-STAT signaling pathway has essential roles in T-cell activation in response to antigen stimulation. Cold Spring Harb Symp Quant Biol 64:291-302

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