Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI028108-09
Application #
2064256
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1988-08-15
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Wong, S B Justin; Siliciano, Robert F (2005) Contribution of virus-like particles to the immunogenicity of human immunodeficiency virus type 1 Gag-derived vaccines in mice. J Virol 79:1701-12
Wong, S B Justin; Buck, Christopher B; Shen, Xuefei et al. (2004) An evaluation of enforced rapid proteasomal degradation as a means of enhancing vaccine-induced CTL responses. J Immunol 173:3073-83
Shen, Xuefei; Wong, S B Justin; Buck, Christopher B et al. (2002) Direct priming and cross-priming contribute differentially to the induction of CD8+ CTL following exposure to vaccinia virus via different routes. J Immunol 169:4222-9
Buck, C B; Shen, X; Egan, M A et al. (2001) The human immunodeficiency virus type 1 gag gene encodes an internal ribosome entry site. J Virol 75:181-91
Ferris, R L; Hall, C; Sipsas, N V et al. (1999) Processing of HIV-1 envelope glycoprotein for class I-restricted recognition: dependence on TAP1/2 and mechanisms for cytosolic localization. J Immunol 162:1324-32
Tobery, T; Siliciano, R F (1999) Cutting edge: induction of enhanced CTL-dependent protective immunity in vivo by N-end rule targeting of a model tumor antigen. J Immunol 162:639-42
Finzi, D; Siliciano, R F (1998) Viral dynamics in HIV-1 infection. Cell 93:665-71
Ray, S C; Lubaki, N; Dhruva, B R et al. (1998) Autologous strain-specific cytolytic T lymphocyte responses directed against human immunodeficiency virus type 1 Env. AIDS Res Hum Retroviruses 14:3-13
Tobery, T W; Siliciano, R F (1997) Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization. J Exp Med 185:909-20
Lubaki, N M; Ray, S C; Dhruva, B et al. (1997) Characterization of a polyclonal cytolytic T lymphocyte response to human immunodeficiency virus in persons without clinical progression. J Infect Dis 175:1360-7

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