Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI030726-14
Application #
6697344
Study Section
Special Emphasis Panel (NSS)
Program Officer
Tseng, Christopher K
Project Start
1990-12-01
Project End
2009-03-31
Budget Start
2004-04-01
Budget End
2005-03-31
Support Year
14
Fiscal Year
2004
Total Cost
$361,311
Indirect Cost
Name
University of Colorado at Boulder
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
007431505
City
Boulder
State
CO
Country
United States
Zip Code
80309
Boots, Jennifer L; Canny, Marella D; Azimi, Ehsan et al. (2008) Metal ion specificities for folding and cleavage activity in the Schistosoma hammerhead ribozyme. RNA 14:2212-22
Canny, Marella D; Jucker, Fiona M; Pardi, Arthur (2007) Efficient ligation of the Schistosoma hammerhead ribozyme. Biochemistry 46:3826-34
Lee, Joon-Hwa; Pardi, Arthur (2007) Thermodynamics and kinetics for base-pair opening in the P1 duplex of the Tetrahymena group I ribozyme. Nucleic Acids Res 35:2965-74
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Sibille, N; Pardi, A; Simorre, J P et al. (2001) Refinement of local and long-range structural order in theophylline-binding RNA using (13)C-(1)H residual dipolar couplings and restrained molecular dynamics. J Am Chem Soc 123:12135-46
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Hansen, M R; Simorre, J P; Hanson, P et al. (1999) Identification and characterization of a novel high affinity metal-binding site in the hammerhead ribozyme. RNA 5:1099-104

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