Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI035705-06
Application #
2631421
Study Section
Special Emphasis Panel (NSS)
Program Officer
Heyse, Stephen P
Project Start
1994-04-01
Project End
2003-12-31
Budget Start
1999-01-01
Budget End
1999-12-31
Support Year
6
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Safo, Martin K; Ko, Tzu Ping; Musayev, Faik N et al. (2006) Structure of the MecI repressor from Staphylococcus aureus in complex with the cognate DNA operator of mec. Acta Crystallogr Sect F Struct Biol Cryst Commun 62:320-4
Safo, Martin K; Zhao, Qixun; Ko, Tzu-Ping et al. (2005) Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons. J Bacteriol 187:1833-44
Wisplinghoff, Hilmar; Rosato, Adriana E; Enright, Mark C et al. (2003) Related clones containing SCCmec type IV predominate among clinically significant Staphylococcus epidermidis isolates. Antimicrob Agents Chemother 47:3574-9
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Mongodin, Emmanuel; Finan, Jon; Climo, Michael W et al. (2003) Microarray transcription analysis of clinical Staphylococcus aureus isolates resistant to vancomycin. J Bacteriol 185:4638-43
McKinney, T K; Sharma, V K; Craig, W A et al. (2001) Transcription of the gene mediating methicillin resistance in Staphylococcus aureus (mecA) is corepressed but not coinduced by cognate mecA and beta-lactamase regulators. J Bacteriol 183:6862-8
Dickinson, T M; Archer, G L (2000) Phenotypic expression of oxacillin resistance in Staphylococcus epidermidis: roles of mecA transcriptional regulation and resistant-subpopulation selection. Antimicrob Agents Chemother 44:1616-23
Archer, G L (1998) Staphylococcus aureus: a well-armed pathogen. Clin Infect Dis 26:1179-81
Climo, M W; Patron, R L; Goldstein, B P et al. (1998) Lysostaphin treatment of experimental methicillin-resistant Staphylococcus aureus aortic valve endocarditis. Antimicrob Agents Chemother 42:1355-60

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