Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI036293-11
Application #
6695327
Study Section
Special Emphasis Panel (NSS)
Program Officer
Beisel, Christopher E
Project Start
1994-08-01
Project End
2009-04-30
Budget Start
2004-05-01
Budget End
2005-04-30
Support Year
11
Fiscal Year
2004
Total Cost
$371,250
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611

  Publications

Aubert, Martine; Yoon, Miri; Sloan, Derek D et al. (2009) The virological synapse facilitates herpes simplex virus entry into T cells. J Virol 83:6171-83
Fan, Qing; Lin, Erick; Spear, Patricia G (2009) Insertional mutations in herpes simplex virus type 1 gL identify functional domains for association with gH and for membrane fusion. J Virol 83:11607-15
Fan, Qing; Lin, Erick; Satoh, Takeshi et al. (2009) Differential effects on cell fusion activity of mutations in herpes simplex virus 1 glycoprotein B (gB) dependent on whether a gD receptor or a gB receptor is overexpressed. J Virol 83:7384-90
Wang, Jing; Fan, Qing; Satoh, Takeshi et al. (2009) Binding of herpes simplex virus glycoprotein B (gB) to paired immunoglobulin-like type 2 receptor alpha depends on specific sialylated O-linked glycans on gB. J Virol 83:13042-5
Cheung, Timothy C; Steinberg, Marcos W; Oborne, Lisa M et al. (2009) Unconventional ligand activation of herpesvirus entry mediator signals cell survival. Proc Natl Acad Sci U S A 106:6244-9
Cheung, Timothy C; Oborne, Lisa M; Steinberg, Marcos W et al. (2009) T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment. J Immunol 183:7286-96
Satoh, Takeshi; Arii, Jun; Suenaga, Tadahiro et al. (2008) PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B. Cell 132:935-44
Lawrence, Roger; Yabe, Tomio; Hajmohammadi, Sassan et al. (2007) The principal neuronal gD-type 3-O-sulfotransferases and their products in central and peripheral nervous system tissues. Matrix Biol 26:442-55
Lin, Erick; Spear, Patricia G (2007) Random linker-insertion mutagenesis to identify functional domains of herpes simplex virus type 1 glycoprotein B. Proc Natl Acad Sci U S A 104:13140-5
Spear, Patricia G; Manoj, Sharmila; Yoon, Miri et al. (2006) Different receptors binding to distinct interfaces on herpes simplex virus gD can trigger events leading to cell fusion and viral entry. Virology 344:17-24

Showing the most recent 10 out of 35 publications