Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI041945-10
Application #
6990925
Study Section
Special Emphasis Panel (NSS)
Program Officer
Sharma, Opendra K
Project Start
1997-08-01
Project End
2011-05-31
Budget Start
2006-06-01
Budget End
2007-05-31
Support Year
10
Fiscal Year
2006
Total Cost
$574,070
Indirect Cost
Name
Aaron Diamond AIDS Research Center
Department
Type
DUNS #
786658872
City
New York
State
NY
Country
United States
Zip Code
10016
Zhuang, Ke; Finzi, Andres; Tasca, Silvana et al. (2011) Adoption of an ""open"" envelope conformation facilitating CD4 binding and structural remodeling precedes coreceptor switch in R5 SHIV-infected macaques. PLoS One 6:e21350
Luchins, Kerith R; Baker, Kate C; Gilbert, Margaret H et al. (2011) Application of the diagnostic evaluation for alopecia in traditional veterinary species to laboratory rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci 50:926-38
Tasca, Silvana; Zhuang, Ke; Gettie, Agegnehu et al. (2011) Effect of B-cell depletion on coreceptor switching in R5 simian-human immunodeficiency virus infection of rhesus macaques. J Virol 85:3086-94
Ren, Wuze; Tasca, Silvana; Zhuang, Ke et al. (2010) Different tempo and anatomic location of dual-tropic and X4 virus emergence in a model of R5 simian-human immunodeficiency virus infection. J Virol 84:340-51
Shakirzyanova, Madina; Ren, Wuze; Zhuang, Ke et al. (2010) Fitness disadvantage of transitional intermediates contributes to dynamic change in the infecting-virus population during coreceptor switch in R5 simian/human immunodeficiency virus-infected macaques. J Virol 84:12862-71
Tasca, Silvana; Ho, Siu-Hong; Cheng-Mayer, Cecilia (2008) R5X4 viruses are evolutionary, functional, and antigenic intermediates in the pathway of a simian-human immunodeficiency virus coreceptor switch. J Virol 82:7089-99
Ho, Siu-hong; Trunova, Nataliya; Gettie, Agegnehu et al. (2008) Different mutational pathways to CXCR4 coreceptor switch of CCR5-using simian-human immunodeficiency virus. J Virol 82:5653-6
Tasca, Silvana; Tsai, Lily; Trunova, Nataliya et al. (2007) Induction of potent local cellular immunity with low dose X4 SHIV(SF33A) vaginal exposure. Virology 367:196-211
Tsai, Lily; Trunova, Nataliya; Gettie, Agegnehu et al. (2007) Efficient repeated low-dose intravaginal infection with X4 and R5 SHIVs in rhesus macaque: implications for HIV-1 transmission in humans. Virology 362:207-16
Ho, Siu-hong; Tasca, Silvana; Shek, Lili et al. (2007) Coreceptor switch in R5-tropic simian/human immunodeficiency virus-infected macaques. J Virol 81:8621-33

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