Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI053102-02
Application #
6684081
Study Section
Immunobiology Study Section (IMB)
Program Officer
Macchiarini, Francesca
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$540,303
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215
Schlenner, Susan M; Weigmann, Benno; Ruan, Qingguo et al. (2012) Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut. J Exp Med 209:1529-35
Daniel, Carolin; Weigmann, Benno; Bronson, Roderick et al. (2011) Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope. J Exp Med 208:1501-10
Daniel, Carolin; Ploegh, Hidde; von Boehmer, Harald (2011) Antigen-specific induction of regulatory T cells in vivo and in vitro. Methods Mol Biol 707:173-85
Daniel, Carolin; von Boehmer, Harald (2011) Extra-thymically induced regulatory T cells: do they have potential in disease prevention? Semin Immunol 23:410-7
Daniel, Carolin; von Boehmer, Harald (2011) Extrathymic generation of regulatory T cells--chances and challenges for prevention of autoimmune disease. Adv Immunol 112:177-213
von Boehmer, Harald; Melchers, Fritz (2010) Checkpoints in lymphocyte development and autoimmune disease. Nat Immunol 11:14-20
Daniel, Carolin; Wennhold, Kerstin; Kim, Hye-Jung et al. (2010) Enhancement of antigen-specific Treg vaccination in vivo. Proc Natl Acad Sci U S A 107:16246-51
Feuerer, Markus; Hill, Jonathan A; Kretschmer, Karsten et al. (2010) Genomic definition of multiple ex vivo regulatory T cell subphenotypes. Proc Natl Acad Sci U S A 107:5919-24
Merkenschlager, Matthias; von Boehmer, Harald (2010) PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors. J Exp Med 207:1347-50
von Boehmer, Harald (2009) Central tolerance: essential for preventing autoimmune disease? Eur J Immunol 39:2313-6

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