Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI059714-16
Application #
9546043
Study Section
Special Emphasis Panel (NSS)
Program Officer
Ferguson, Stacy E
Project Start
2019-02-01
Project End
2021-01-31
Budget Start
2019-02-01
Budget End
2020-01-31
Support Year
16
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
781613492
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Gavin, Amanda L; Huang, Deli; Huber, Christoph et al. (2018) PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing. Nat Immunol 19:942-953
Nemazee, David (2017) Mechanisms of central tolerance for B cells. Nat Rev Immunol 17:281-294
Martinic, Marianne M; Caminschi, Irina; O'Keeffe, Meredith et al. (2017) The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection. J Immunol 198:2649-2660
Lai, Maoyi; Gonzalez-Martin, Alicia; Cooper, Anthony B et al. (2016) Regulation of B-cell development and tolerance by different members of the miR-17?92 family microRNAs. Nat Commun 7:12207
Lang, Julie; Ota, Takayuki; Kelly, Margot et al. (2016) Receptor editing and genetic variability in human autoreactive B cells. J Exp Med 213:93-108
Gonzalez-Martin, Alicia; Adams, Brian D; Lai, Maoyi et al. (2016) The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity. Nat Immunol 17:433-40
Aït-Azzouzene, Djemel; Kono, Dwight H; Gonzalez-Quintial, Rosana et al. (2010) Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice. J Immunol 185:1015-27