Regulation of T-cell function and autoimmune inflammation by deubiquitinases.

Sun, Shao-Cong

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 4R37AI064639-15
• Application #: 9843180
• Study Section: Special Emphasis Panel (NSS)
• Program Officer: Jiang, Chao
• Project Start: 2006-07-01
• Project End: 2025-06-30
• Budget Start: 2020-07-01
• Budget End: 2021-06-30
• Support Year: 15
• Fiscal Year: 2020

Institution

• Name: University of Texas MD Anderson Cancer Center
• DUNS #: 800772139
• City: Houston
• State: TX
• Country: United States
• Zip Code: 77030

Publications

Shi, Jian-Hong; Sun, Shao-Cong (2018) Tumor Necrosis Factor Receptor-Associated Factor Regulation of Nuclear Factor ?B and Mitogen-Activated Protein Kinase Pathways. Front Immunol 9:1849

Shi, Jian-Hong; Xie, Xiaoping; Sun, Shao-Cong (2018) TBK1 as a regulator of autoimmunity and antitumor immunity. Cell Mol Immunol 15:743-745

Yu, Xiaoyan; Teng, Xiao-Lu; Wang, Feixiang et al. (2018) Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome. J Exp Med 215:2463-2476

Zhu, Lele; Xie, Xiaoping; Zhang, Lingyun et al. (2018) TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun 9:2812

Jie, Zuliang; Yang, Jin-Young; Gu, Meidi et al. (2018) NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis. Nat Immunol 19:1224-1235

Yang, Jie; Zhang, Siya; Zhang, Lingyun et al. (2018) Lymphatic endothelial cells regulate B-cell homing to lymph nodes via a NIK-dependent mechanism. Cell Mol Immunol :

Kumar, Amrendra; Suryadevara, Naveenchandra; Hill, Timothy M et al. (2017) Natural Killer T Cells: An Ecological Evolutionary Developmental Biology Perspective. Front Immunol 8:1858

Sun, Shao-Cong (2017) The non-canonical NF-?B pathway in immunity and inflammation. Nat Rev Immunol 17:545-558

Liu, Ting; Zhang, Lingyun; Joo, Donghyun et al. (2017) NF-?B signaling in inflammation. Signal Transduct Target Ther 2:

Wang, Bin; Jie, Zuliang; Joo, Donghyun et al. (2017) TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature 545:365-369