Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AR012849-27
Application #
2078299
Study Section
Special Emphasis Panel (NSS)
Project Start
1975-10-01
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
27
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Starkebaum, G; Shasteen, N M; Fleming-Jones, R M et al. (1996) Sera of patients with rheumatoid arthritis contain antibodies to recombinant human T-lymphotrophic virus type I/II envelope glycoprotein p21. Clin Immunol Immunopathol 79:182-8
Mannik, M; Person, R E (1993) Immunoglobulin G and serum albumin isolated from the articular cartilage of patients with rheumatoid arthritis or osteoarthritis contain covalent heteropolymers with proteoglycans. Rheumatol Int 13:121-9
Hillson, J L; Oppliger, I R; Sasso, E H et al. (1992) Emerging human B cell repertoire. Influence of developmental stage and interindividual variation. J Immunol 149:3741-52
Trujillo, P E; Mannik, M (1992) IgG is bound by antigen-antibody bonds and some IgG and albumin are bound by intermolecular disulfide bonds to cartilage in rheumatoid arthritis and osteoarthritis. Rheumatol Int 11:225-34
Mannik, M (1992) Rheumatoid factors in the pathogenesis of rheumatoid arthritis. J Rheumatol Suppl 32:46-9
Sasso, E H; Silverman, G J; Mannik, M (1991) Human IgA and IgG F(ab')2 that bind to staphylococcal protein A belong to the VHIII subgroup. J Immunol 147:1877-83
Mannik, M; Person, R E (1991) New antigenic determinants revealed on human IgG by binding to immunoblotting membranes [corrected] J Immunol Methods 144:265-7
Watts, R A; Hillson, J L; Oppliger, I R et al. (1991) Sequence analysis and idiotypic relationships of BEG-2, a human fetal antibody reactive with DNA. Lupus 1:9-17
Vetto, A A; Mannik, M; Zatarain-Rios, E et al. (1990) Immune deposits in articular cartilage of patients with rheumatoid arthritis have a granular pattern not seen in osteoarthritis. Rheumatol Int 10:13-9
Johansson, P J; Nardella, F A; Sjoquist, J et al. (1989) Herpes simplex type 1-induced Fc receptor binds to the Cgamma2-Cgamma3 interface region of IgG in the area that binds staphylococcal protein A. Immunology 66:8-13

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