Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AR017346-23
Application #
2078365
Study Section
Special Emphasis Panel (NSS)
Project Start
1974-09-01
Project End
2000-02-29
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
23
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brandeis University
Department
Type
Organized Research Units
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
02454
Gillilan, Richard E; Kumar, V S Senthil; O'Neall-Hennessey, Elizabeth et al. (2013) X-ray solution scattering of squid heavy meromyosin: strengthening the evidence for an ancient compact off state. PLoS One 8:e81994
O'Neall-Hennessey, Elizabeth; Reshetnikova, Ludmila; Senthil Kumar, V S et al. (2013) Purification, crystallization and preliminary X-ray crystallographic analysis of squid heavy meromyosin. Acta Crystallogr Sect F Struct Biol Cryst Commun 69:248-52
Brown, Jerry H (2013) Deriving how far structural information is transmitted through parallel homodimeric coiled-coils: a correlation analysis of helical staggers. Proteins 81:635-43
Kumar, V S Senthil; O'Neall-Hennessey, Elizabeth; Reshetnikova, Ludmila et al. (2011) Crystal structure of a phosphorylated light chain domain of scallop smooth-muscle myosin. Biophys J 101:2185-9
Brown, Jerry H; Kumar, V S Senthil; O'Neall-Hennessey, Elizabeth et al. (2011) Visualizing key hinges and a potential major source of compliance in the lever arm of myosin. Proc Natl Acad Sci U S A 108:114-9
Rosenbluth, Jack; Szent-Gyorgyi, Andrew G; Thompson, Joseph T (2010) The ultrastructure and contractile properties of a fast-acting, obliquely striated, myosin-regulated muscle: the funnel retractor of squids. J Exp Biol 213:2430-43
Brown, Jerry H (2010) How sequence directs bending in tropomyosin and other two-stranded alpha-helical coiled coils. Protein Sci 19:1366-75
Himmel, Daniel M; Mui, Suet; O'Neall-Hennessey, Elizabeth et al. (2009) The on-off switch in regulated myosins: different triggers but related mechanisms. J Mol Biol 394:496-505
Yang, Yuting; Gourinath, S; Kovacs, Mihaly et al. (2007) Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure 15:553-64
Szent-Gyorgyi, Andrew G (2007) Regulation by myosin: how calcium regulates some myosins, past and present. Adv Exp Med Biol 592:253-64

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