Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AR030102-16
Application #
2078677
Study Section
General Medicine B Study Section (GMB)
Project Start
1981-07-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Chatterjee, Oindrila; Nakchbandi, Inaam A; Philbrick, William M et al. (2002) Endogenous parathyroid hormone-related protein functions as a neuroprotective agent. Brain Res 930:58-66
Brines, M L; Broadus, A E (1999) Parathyroid hormone-related protein markedly potentiates depolarization-induced catecholamine release in PC12 cells via L-type voltage-sensitive Ca2+ channels. Endocrinology 140:646-51
Brines, M L; Ling, Z; Broadus, A E (1999) Parathyroid hormone-related protein protects against kainic acid excitotoxicity in rat cerebellar granule cells by regulating L-type channel calcium flux. Neurosci Lett 274:13-6
Wysolmerski, J J; Philbrick, W M; Dunbar, M E et al. (1998) Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. Development 125:1285-94
Philbrick, W M (1998) Parathyroid hormone-related protein is a developmental regulatory molecule. Eur J Oral Sci 106 Suppl 1:32-7
Philbrick, W M; Dreyer, B E; Nakchbandi, I A et al. (1998) Parathyroid hormone-related protein is required for tooth eruption. Proc Natl Acad Sci U S A 95:11846-51
Foley, J; Longely, B J; Wysolmerski, J J et al. (1998) PTHrP regulates epidermal differentiation in adult mice. J Invest Dermatol 111:1122-8
Amling, M; Neff, L; Tanaka, S et al. (1997) Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development. J Cell Biol 136:205-13
Vasavada, R C; Cavaliere, C; D'Ercole, A J et al. (1996) Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia. J Biol Chem 271:1200-8
Philbrick, W M; Wysolmerski, J J; Galbraith, S et al. (1996) Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol Rev 76:127-73

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