Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37AR032063-10S1
Application #
3481549
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1991-02-15
Project End
1991-12-31
Budget Start
1991-02-15
Budget End
1991-12-31
Support Year
10
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Ochs, R L; Muro, Y; Si, Y et al. (2000) Autoantibodies to DFS 70 kd/transcription coactivator p75 in atopic dermatitis and other conditions. J Allergy Clin Immunol 105:1211-20
Pollard, K M; Pearson, D L; Bluthner, M et al. (2000) Proteolytic cleavage of a self-antigen following xenobiotic-induced cell death produces a fragment with novel immunogenic properties. J Immunol 165:2263-70
Zhang, J Y; Chan, E K; Peng, X X et al. (1999) A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. J Exp Med 189:1101-10
Erlanson, M; Casiano, C A; Tan, E M et al. (1999) Immunohistochemical analysis of the proliferation associated nuclear antigen CENP-F in non-Hodgkin's lymphoma. Mod Pathol 12:69-74
Furuta, K; Hildebrandt, B; Matsuoka, S et al. (1998) Immunological characterization of heterochromatin protein p25beta autoantibodies and relationship with centromere autoantibodies and pulmonary fibrosis in systemic scleroderma. J Mol Med 76:54-60
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Pollard, K M; Lee, D K; Casiano, C A et al. (1997) The autoimmunity-inducing xenobiotic mercury interacts with the autoantigen fibrillarin and modifies its molecular and antigenic properties. J Immunol 158:3521-8
Covini, G; von Muhlen, C A; Pacchetti, S et al. (1997) Diversity of antinuclear antibody responses in hepatocellular carcinoma. J Hepatol 26:1255-65
Andrade, L E; Chan, E K; Peebles, C L et al. (1996) Two major autoantigen-antibody systems of the mitotic spindle apparatus. Arthritis Rheum 39:1643-53
Casiano, C A; Tan, E M (1996) Antinuclear autoantibodies: probes for defining proteolytic events associated with apoptosis. Mol Biol Rep 23:211-6

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