Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37CA004946-26S1
Application #
3481596
Study Section
Immunobiology Study Section (IMB)
Project Start
1983-12-01
Project End
1991-11-30
Budget Start
1986-12-01
Budget End
1987-11-30
Support Year
26
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Institute for Cancer Research
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Nakajima, Pamela B; Kiefer, Kerstin; Price, Amy et al. (2009) Two distinct populations of H chain-edited B cells show differential surrogate L chain dependence. J Immunol 182:3583-96
Kiefer, Kerstin; Nakajima, Pamela B; Oshinsky, Jennifer et al. (2008) Antigen receptor editing in anti-DNA transitional B cells deficient for surface IgM. J Immunol 180:6094-106
Bosma, Gayle C; Oshinsky, Jennifer; Kiefer, Kerstin et al. (2006) Development of functional B cells in a line of SCID mice with transgenes coding for anti-double-stranded DNA antibody. J Immunol 176:889-98
Bosma, Gayle C; Kim, Jiyoon; Urich, Teresa et al. (2002) DNA-dependent protein kinase activity is not required for immunoglobulin class switching. J Exp Med 196:1483-95
Nakajima, Pamela B; Bosma, Melvin J (2002) Variable diversity joining recombination: nonhairpin coding ends in thymocytes of SCID and wild-type mice. J Immunol 169:3094-104
Ruetsch, N R; Bosma, G C; Bosma, M J (2000) Unexpected rearrangement and expression of the immunoglobulin lambda1 locus in scid mice. J Exp Med 191:1933-43
Bosma, G C; Chang, Y; Karasuyama, H et al. (1999) Differential effect of an Ig mu transgene on development of pre-B cells in fetal and adult SCID mice. Proc Natl Acad Sci U S A 96:11952-7
Wiest, D L; Berger, M A; Carleton, M (1999) Control of early thymocyte development by the pre-T cell receptor complex: A receptor without a ligand? Semin Immunol 11:251-62
Chang, Y; Bosma, M J; Bosma, G C (1999) Extended duration of DH-JH rearrangement in immunoglobulin heavy chain transgenic mice: implications for regulation of allelic exclusion. J Exp Med 189:1295-305
Chang, Y; Bosma, M J (1997) Effect of different Ig transgenes on B cell differentiation in scid mice. Int Immunol 9:373-80

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