Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37CA013311-25
Application #
2086122
Study Section
Special Emphasis Panel (NSS)
Project Start
1975-10-01
Project End
1998-11-30
Budget Start
1995-12-20
Budget End
1996-11-30
Support Year
25
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Kozin, Sergey V; Niemierko, Andrzej; Huang, Peigen et al. (2008) Inter- and intramouse heterogeneity of radiation response for a growing paired organ. Radiat Res 170:264-7
Pardo, F S; Hsu, D W; Zeheb, R et al. (2004) Mutant, wild type, or overall p53 expression: freedom from clinical progression in tumours of astrocytic lineage. Br J Cancer 91:1678-86
Kozin, S V; Shkarin, P; Gerweck, L E (2001) The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics. Cancer Res 61:4740-3
Chastagner, P; Kozin, S V; Taghian, A (2001) Topotecan selectively enhances the radioresponse of human small-cell lung carcinoma and glioblastoma multiforme xenografts in nude mice. Int J Radiat Oncol Biol Phys 50:777-82
Hartford, A C; Gohongi, T; Fukumura, D et al. (2000) Irradiation of a primary tumor, unlike surgical removal, enhances angiogenesis suppression at a distal site: potential role of host-tumor interaction. Cancer Res 60:2128-31
Griffon-Etienne, G; Boucher, Y; Brekken, C et al. (1999) Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications. Cancer Res 59:3776-82
Budach, W; Gioioso, D; Taghian, A et al. (1997) Repopulation capacity during fractionated irradiation of squamous cell carcinomas and glioblastomas in vitro. Int J Radiat Oncol Biol Phys 39:743-50
Griffon-Etienne, G; Boucher, Y; Jain, R K et al. (1997) Effects of needle insertion in tumors on interstitial fluid pressure. Microvasc Res 54:174-7
Huang, P; Taghian, A; Hsu, D W et al. (1996) Spontaneous metastasis, proliferation characteristics and radiation sensitivity of fractionated irradiation recurrent and unirradiated human xenografts. Radiother Oncol 41:73-81
Huang, P; Taghian, A; Allam, A et al. (1996) The effect of whole-body irradiation of nude mice on the tumor transplantability and control probability of a human soft tissue sarcoma xenograft. Radiat Res 145:337-42

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