Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA022247-19
Application #
2087028
Study Section
Special Emphasis Panel (NSS)
Project Start
1977-08-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1998-03-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
New York University
Department
Pathology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Tseng, Jen-Chieh; Zanzonico, Pat B; Levin, Brandi et al. (2006) Tumor-specific in vivo transfection with HSV-1 thymidine kinase gene using a Sindbis viral vector as a basis for prodrug ganciclovir activation and PET. J Nucl Med 47:1136-43
Hurtado, Alicia; Tseng, Jen-Chieh; Meruelo, Daniel (2006) Gene therapy that safely targets and kills tumor cells throughout the body. Rejuvenation Res 9:36-44
Hurtado, Alicia; Tseng, Jen-Chieh; Boivin, Christopher et al. (2005) Identification of amino acids of Sindbis virus E2 protein involved in targeting tumor metastases in vivo. Mol Ther 12:813-23
Tseng, Jen-Chieh; Hurtado, Alicia; Yee, Herman et al. (2004) Using sindbis viral vectors for specific detection and suppression of advanced ovarian cancer in animal models. Cancer Res 64:6684-92
Tseng, Jen-Chieh; Levin, Brandi; Hurtado, Alicia et al. (2004) Systemic tumor targeting and killing by Sindbis viral vectors. Nat Biotechnol 22:70-7
Tseng, Jen-Chieh; Levin, Brandi; Hirano, Tadamichi et al. (2002) In vivo antitumor activity of Sindbis viral vectors. J Natl Cancer Inst 94:1790-802
Choi, Jung W; Pampeno, Christine; Vukmanovic, Stanislav et al. (2002) Characterization of the transcriptional expression of Notch-1 signaling pathway members, Deltex and HES-1, in developing mouse thymocytes. Dev Comp Immunol 26:575-88
Pampeno, C L; Vallerie, A M; Choi, J et al. (2001) Genomic analysis and localization of murine Deltex, a modulator of notch activity, to mouse chromosome 5 and its human homolog to chromosome 12. DNA Cell Biol 20:141-8
Ishizu, A; Sawai, K; Ikeda, H et al. (2000) Transduction of a murine dominant negative activation transcription factor 1 increases cell surface expression of the class I MHC on a human epidermoid tumor cell line. Int Immunol 12:161-8
Yu, A; Choi, J; Ohno, K et al. (2000) Specific cell targeting for delivery of toxins into small-cell lung cancer using a streptavidin fusion protein complex. DNA Cell Biol 19:383-8

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