Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37CA023226-35
Application #
6926494
Study Section
Special Emphasis Panel (NSS)
Program Officer
Spalholz, Barbara A
Project Start
1977-08-01
Project End
2009-01-31
Budget Start
2006-04-01
Budget End
2007-01-31
Support Year
35
Fiscal Year
2006
Total Cost
$388,750
Indirect Cost

  Institution

Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Wright, Jocelyn H; Johnson, Melissa M; Shimizu-Albergine, Masami et al. (2014) Paracrine activation of hepatic stellate cells in platelet-derived growth factor C transgenic mice: evidence for stromal induction of hepatocellular carcinoma. Int J Cancer 134:778-88
Riehle, Kimberly J; Johnson, Melissa M; Johansson, Fredrik et al. (2014) Tissue-type plasminogen activator is not necessary for platelet-derived growth factor-c activation. Biochim Biophys Acta 1842:318-25
Obayashi, Yoko; Campbell, Jean S; Fausto, Nelson et al. (2013) Impaired lipid accumulation in the liver of Tsc2-heterozygous mice during liver regeneration. Biochem Biophys Res Commun 437:146-50
Riehle, Kimberly J; Haque, Jamil; McMahan, Ryan S et al. (2013) Sustained Glutathione Deficiency Interferes with the Liver Response to TNF-? and Liver Regeneration after Partial Hepatectomy in Mice. J Liver Disease Transplant 1:
McMahan, Ryan S; Riehle, Kimberly J; Fausto, Nelson et al. (2013) A disintegrin and metalloproteinase 17 regulates TNF and TNFR1 levels in inflammation and liver regeneration in mice. Am J Physiol Gastrointest Liver Physiol 305:G25-34
Fernando, Joan; Sancho, Patricia; Fernandez-Rodriguez, Conrado M et al. (2012) Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli. J Cell Physiol 227:1319-25
Okada, Hikari; Honda, Masao; Campbell, Jean S et al. (2012) Acyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma development. Cancer Res 72:4459-71
Caja, Laia; Bertran, Esther; Campbell, Jean et al. (2011) The transforming growth factor-beta (TGF-?) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells. J Cell Physiol 226:1214-23
Riehle, Kimberly J; Dan, Yock Y; Campbell, Jean S et al. (2011) New concepts in liver regeneration. J Gastroenterol Hepatol 26 Suppl 1:203-12
Caja, Laia; Sancho, Patricia; Bertran, Esther et al. (2011) The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms. Biochem Pharmacol 82:1583-92

Showing the most recent 10 out of 85 publications