Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA023296-13
Application #
3481958
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1978-04-01
Project End
1990-09-30
Budget Start
1990-04-01
Budget End
1990-09-30
Support Year
13
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065

  Publications

Traganos, F; Darzynkiewicz, Z (1994) Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations. Methods Cell Biol 41:185-94
Darzynkiewicz, Z; Gorczyca, W; Lassota, P et al. (1993) Altered sensitivity of DNA in situ to denaturation in apoptotic cells. Ann N Y Acad Sci 677:334-40
Gorczyca, W; Melamed, M R; Darzynkiewicz, Z (1993) Apoptosis of S-phase HL-60 cells induced by DNA topoisomerase inhibitors: detection of DNA strand breaks by flow cytometry using the in situ nick translation assay. Toxicol Lett 67:249-58
Kapuscinski, J; Kimmel, M (1993) Thermodynamical model of mixed aggregation of intercalators with caffeine in aqueous solution. Biophys Chem 46:153-63
Hotz, M A; Traganos, F; Darzynkiewicz, Z (1992) Changes in nuclear chromatin related to apoptosis or necrosis induced by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation. Exp Cell Res 201:184-91
Bruno, S; Ardelt, B; Skierski, J S et al. (1992) Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes. Cancer Res 52:470-3
Hotz, M A; Del Bino, G; Lassota, P et al. (1992) Cytostatic and cytotoxic effects of fostriecin on human promyelocytic HL-60 and lymphocytic MOLT-4 leukemic cells. Cancer Res 52:1530-5
Gorczyca, W; Bruno, S; Melamed, M R et al. (1992) Cell cycle-related expression of p120 nucleolar antigen in normal human lymphocytes and in cells of HL-60 and MOLT-4 leukemic lines: effects of methotrexate, camptothecin, and teniposide. Cancer Res 52:3491-4
Del Bino, G; Bruno, S; Yi, P N et al. (1992) Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation. Cell Prolif 25:537-48
Darzynkiewicz, Z; Bruno, S; Del Bino, G et al. (1992) Features of apoptotic cells measured by flow cytometry. Cytometry 13:795-808

Showing the most recent 10 out of 75 publications