Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA025917-17
Application #
2087426
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-08-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1998-01-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Utah
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Zhang, Tian Y; Ding, Xiaohong; Daynes, Raymond A (2005) The expression of 11 beta-hydroxysteroid dehydrogenase type I by lymphocytes provides a novel means for intracrine regulation of glucocorticoid activities. J Immunol 174:879-89
Jones, Dallas C; Ding, Xiaohong; Zhang, Tian Y et al. (2003) Peroxisome proliferator-activated receptor alpha negatively regulates T-bet transcription through suppression of p38 mitogen-activated protein kinase activation. J Immunol 171:196-203
Daynes, Raymond A; Enioutina, Elena Y; Jones, Dallas C (2003) Role of redox imbalance in the molecular mechanisms responsible for immunosenescence. Antioxid Redox Signal 5:537-48
Enioutina, Elena Y; Visic, Dino M; Daynes, Raymond A (2002) The induction of systemic and mucosal immunity to protein vaccines delivered through skin sites exposed to UVB. Vaccine 20:2116-30
Jones, Dallas C; Manning, Bernadette M; Daynes, Raymond A (2002) A role for the peroxisome proliferator-activated receptor alpha in T-cell physiology and ageing immunobiology. Proc Nutr Soc 61:363-9
Jones, Dallas C; Ding, Xiaohong; Daynes, Raymond A (2002) Nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) is expressed in resting murine lymphocytes. The PPARalpha in T and B lymphocytes is both transactivation and transrepression competent. J Biol Chem 277:6838-45
Heithoff, D M; Enioutina, E Y; Daynes, R A et al. (2001) Salmonella DNA adenine methylase mutants confer cross-protective immunity. Infect Immun 69:6725-30
Manning, B M; Enioutina, E Y; Visic, D M et al. (2001) CpG DNA functions as an effective adjuvant for the induction of immune responses in aged mice. Exp Gerontol 37:107-26
Enioutina, E Y; Visic, V D; Daynes, R A (2000) Enhancement of common mucosal immunity in aged mice following their supplementation with various antioxidants. Vaccine 18:2381-93
Chen, X P; Ding, X; Daynes, R A (2000) Ganglioside control over IL-4 priming and cytokine production in activated T cells. Cytokine 12:972-85

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