Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA031230-14
Application #
2088122
Study Section
Special Emphasis Panel (NSS)
Project Start
1982-03-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Children's Hospital of Los Angeles
Department
Type
DUNS #
094878337
City
Los Angeles
State
CA
Country
United States
Zip Code
90027
Fisher, A M; Rucker, N; Wong, S et al. (1998) Differential photosensitivity in wild-type and mutant p53 human colon carcinoma cell lines. J Photochem Photobiol B 42:104-7
Fisher, A M; Danenberg, K; Banerjee, D et al. (1997) Increased photosensitivity in HL60 cells expressing wild-type p53. Photochem Photobiol 66:265-70
Gomer, C J; Ryter, S W; Ferrario, A et al. (1996) Photodynamic therapy-mediated oxidative stress can induce expression of heat shock proteins. Cancer Res 56:2355-60
Gomer, C J; Luna, M; Ferrario, A et al. (1996) Cellular targets and molecular responses associated with photodynamic therapy. J Clin Laser Med Surg 14:315-21
Luna, M C; Ferrario, A; Rucker, N et al. (1995) Decreased expression and function of alpha-2 macroglobulin receptor/low density lipoprotein receptor-related protein in photodynamic therapy-resistant mouse tumor cells. Cancer Res 55:1820-3
Luna, M C; Wong, S; Gomer, C J (1994) Photodynamic therapy mediated induction of early response genes. Cancer Res 54:1374-80
Ryter, S W; Gomer, C J (1993) Nuclear factor kappa B binding activity in mouse L1210 cells following photofrin II-mediated photosensitization. Photochem Photobiol 58:753-6
Fisher, A M; Ferrario, A; Gomer, C J (1993) Adriamycin resistance in Chinese hamster fibroblasts following oxidative stress induced by photodynamic therapy. Photochem Photobiol 58:581-8
Li, L J; Li, X; Ferrario, A et al. (1992) Establishment of a Chinese hamster ovary cell line that expresses grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94. J Cell Physiol 153:575-82
Ferrario, A; Kessel, D; Gomer, C J (1992) Metabolic properties and photosensitizing responsiveness of mono-L-aspartyl chlorin e6 in a mouse tumor model. Cancer Res 52:2890-3

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