Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37CA034722-14
Application #
2088740
Study Section
Special Emphasis Panel (NSS)
Project Start
1983-04-03
Project End
1999-03-31
Budget Start
1996-04-20
Budget End
1997-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Pores Fernando, A T; Andrabi, S; Cizmecioglu, O et al. (2015) Polyoma small T antigen triggers cell death via mitotic catastrophe. Oncogene 34:2483-92
Utermark, Tamara; Schmit, Fabienne; Lee, Sang Hyun et al. (2014) The phosphatidylinositol 3-kinase (PI3K) isoform dependence of tumor formation is determined by the genetic mode of PI3K pathway activation rather than by tissue type. J Virol 88:10673-9
Hwang, Justin H; Pores Fernando, Arun T; Faure, Nathalie et al. (2014) Polyomavirus small T antigen interacts with yes-associated protein to regulate cell survival and differentiation. J Virol 88:12055-64
Harrison, Celia; Jiang, Tao; Banerjee, Pubali et al. (2013) Polyomavirus large T antigen binds symmetrical repeats at the viral origin in an asymmetrical manner. J Virol 87:13751-9
Banerjee, Pubali; DeJesus, Rowena; Gjoerup, Ole et al. (2013) Viral interference with DNA repair by targeting of the single-stranded DNA binding protein RPA. PLoS Pathog 9:e1003725
Andrabi, Shaida; Hwang, Justin H; Choe, Jennifer Kean et al. (2011) Comparisons between murine polyomavirus and Simian virus 40 show significant differences in small T antigen function. J Virol 85:10649-58
Gjoerup, Ole V; Wu, Jiaping; Chandler-Militello, Devin et al. (2007) Surveillance mechanism linking Bub1 loss to the p53 pathway. Proc Natl Acad Sci U S A 104:8334-9
Utermark, Tamara; Schaffhausen, Brian S; Roberts, Thomas M et al. (2007) The p110alpha isoform of phosphatidylinositol 3-kinase is essential for polyomavirus middle T antigen-mediated transformation. J Virol 81:7069-76
Andrabi, Shaida; Gjoerup, Ole V; Kean, Jennifer A et al. (2007) Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner. Proc Natl Acad Sci U S A 104:19011-6
Whalen, Kerry A; de Jesus, Rowena; Kean, Jennifer A et al. (2005) Genetic analysis of the polyomavirus DnaJ domain. J Virol 79:9982-90

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