Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA036327-13
Application #
2089086
Study Section
Pathology B Study Section (PTHB)
Project Start
1984-01-01
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
New York University
Department
Pathology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Lynch, Stephen J; Zavadil, Jiri; Pellicer, Angel (2014) In TCR-stimulated T-cells, N-ras regulates specific genes and signal transduction pathways. PLoS One 8:e63193
Benet, Marta; Dulman, Robin Yates; Suzme, Raffi et al. (2012) Wild type N-ras displays anti-malignant properties, in part by downregulating decorin. J Cell Physiol 227:2341-51
Osei-Sarfo, Kwame; de Castro, Ignacio Perez; Pellicer, Angel (2012) p15(INK4b) plays a crucial role in murine lymphoid development and tumorigenesis. Carcinogenesis 33:708-13
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Perez de Castro, Ignacio; Benet, Marta; Jimenez, Maria et al. (2005) Mouse p10, an alternative spliced form of p15INK4b, inhibits cell cycle progression and malignant transformation. Cancer Res 65:3249-56
Diaz, Roberto; Lue, Jeffrey; Mathews, Jeremy et al. (2005) Inhibition of Ras oncogenic activity by Ras protooncogenes. Int J Cancer 113:241-8
Perez de Castro, Ignacio; Bivona, Trever G; Philips, Mark R et al. (2004) Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus. Mol Cell Biol 24:3485-96
Diaz, Roberto; Lopez-Barcons, Lluis; Ahn, Daniel et al. (2004) Complex effects of Ras proto-oncogenes in tumorigenesis. Carcinogenesis 25:535-9
Corral, Teresa; Jimenez, Maria; Hernandez-Munoz, Inmaculada et al. (2003) NF1 modulates the effects of Ras oncogenes: evidence of other NF1 function besides its GAP activity. J Cell Physiol 197:214-24
Perez de Castro, Ignacio; Diaz, Roberto; Malumbres, Marcos et al. (2003) Mice deficient for N-ras: impaired antiviral immune response and T-cell function. Cancer Res 63:1615-22

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