Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37CA040414-16
Application #
6042105
Study Section
Special Emphasis Panel (NSS)
Program Officer
Read-Connole, Elizabeth Lee
Project Start
1985-07-01
Project End
2003-04-30
Budget Start
2000-06-09
Budget End
2001-04-30
Support Year
16
Fiscal Year
2000
Total Cost
$357,863
Indirect Cost
Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Dai, Jianli; Chuang, Ray-Yuan; Kelly, Thomas J (2005) DNA replication origins in the Schizosaccharomyces pombe genome. Proc Natl Acad Sci U S A 102:337-42
Vashee, S; Simancek, P; Challberg, M D et al. (2001) Assembly of the human origin recognition complex. J Biol Chem 276:26666-73
Moarefi, I F; Small, D; Gilbert, I et al. (1993) Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding. J Virol 67:4992-5002
Virshup, D M; Russo, A A; Kelly, T J (1992) Mechanism of activation of simian virus 40 DNA replication by protein phosphatase 2A. Mol Cell Biol 12:4883-95
Randall, S K; Kelly, T J (1992) The fate of parental nucleosomes during SV40 DNA replication. J Biol Chem 267:14259-65
Scheidtmann, K H; Virshup, D M; Kelly, T J (1991) Protein phosphatase 2A dephosphorylates simian virus 40 large T antigen specifically at residues involved in regulation of DNA-binding activity. J Virol 65:2098-101
Erdile, L F; Collins, K L; Russo, A et al. (1991) Initiation of SV40 DNA replication: mechanism and control. Cold Spring Harb Symp Quant Biol 56:303-13
Weinberg, D H; Collins, K L; Simancek, P et al. (1990) Reconstitution of simian virus 40 DNA replication with purified proteins. Proc Natl Acad Sci U S A 87:8692-6
Virshup, D M; Kauffman, M G; Kelly, T J (1989) Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A. EMBO J 8:3891-8
Cheng, L; Kelly, T J (1989) Transcriptional activator nuclear factor I stimulates the replication of SV40 minichromosomes in vivo and in vitro. Cell 59:541-51

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