Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA040586-11
Application #
2090274
Study Section
Special Emphasis Panel (NSS)
Project Start
1985-07-01
Project End
1997-03-31
Budget Start
1995-07-01
Budget End
1997-03-31
Support Year
11
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Rathi, Abhilasha V; Cantalupo, Paul G; Sarkar, Saumendra N et al. (2010) Induction of interferon-stimulated genes by Simian virus 40 T antigens. Virology 406:202-11
Cantalupo, Paul G; Sáenz-Robles, Maria Teresa; Rathi, Abhilasha V et al. (2009) Cell-type specific regulation of gene expression by simian virus 40 T antigens. Virology 386:183-91
Pipas, James M (2009) SV40: Cell transformation and tumorigenesis. Virology 384:294-303
Ahuja, Deepika; Rathi, Abhilasha V; Greer, Amy E et al. (2009) A structure-guided mutational analysis of simian virus 40 large T antigen: identification of surface residues required for viral replication and transformation. J Virol 83:8781-8
Saenz-Robles, M T; Toma, D; Cantalupo, P et al. (2007) Repression of intestinal drug metabolizing enzymes by the SV40 large T antigen. Oncogene 26:5124-31
Ahuja, Deepika; Saenz-Robles, M Teresa; Pipas, James M (2005) SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation. Oncogene 24:7729-45
Cantalupo, Paul; Doering, Adrienne; Sullivan, Christopher S et al. (2005) Complete nucleotide sequence of polyomavirus SA12. J Virol 79:13094-104
Markovics, Jennifer A; Carroll, Patrick A; Robles, M Teresa Saenz et al. (2005) Intestinal dysplasia induced by simian virus 40 T antigen is independent of p53. J Virol 79:7492-502
Sullivan, C S; Baker, A E; Pipas, J M (2004) Simian virus 40 infection disrupts p130-E2F and p107-E2F complexes but does not perturb pRb-E2F complexes. Virology 320:218-28
Chromy, Laura R; Pipas, James M; Garcea, Robert L (2003) Chaperone-mediated in vitro assembly of Polyomavirus capsids. Proc Natl Acad Sci U S A 100:10477-82

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