Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37CA042742-12
Application #
2090913
Study Section
Special Emphasis Panel (NSS)
Project Start
1985-11-01
Project End
1999-12-31
Budget Start
1996-02-09
Budget End
1996-12-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rutgers University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Matsumura, Fumio; Yamakita, Yoshihiko; Yamashiro, Shigeko (2011) Myosin phosphatase-targeting subunit 1 controls chromatid segregation. J Biol Chem 286:10825-33
Yamakita, Yoshihiko; Matsumura, Fumio; Yamashiro, Shigeko (2009) Fascin1 is dispensable for mouse development but is favorable for neonatal survival. Cell Motil Cytoskeleton 66:524-34
Yamashiro, Shigeko; Yamakita, Yoshihiko; Totsukawa, Go et al. (2008) Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1. Dev Cell 14:787-97
Takiguchi, Kingo; Matsumura, Fumio (2005) Role of the basic C-terminal half of caldesmon in its regulation of F-actin: comparison between caldesmon and calponin. J Biochem 138:805-13
Totsukawa, Go; Wu, Yue; Sasaki, Yasuharu et al. (2004) Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J Cell Biol 164:427-39
Yamashiro, Shigeko; Totsukawa, Go; Yamakita, Yoshihiko et al. (2003) Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II. Mol Biol Cell 14:1745-56
Ward, Yvona; Yap, Seow-Fong; Ravichandran, V et al. (2002) The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway. J Cell Biol 157:291-302
Yamashiro, S; Chern, H; Yamakita, Y et al. (2001) Mutant Caldesmon lacking cdc2 phosphorylation sites delays M-phase entry and inhibits cytokinesis. Mol Biol Cell 12:239-50
Cohan, C S; Welnhofer, E A; Zhao, L et al. (2001) Role of the actin bundling protein fascin in growth cone morphogenesis: localization in filopodia and lamellipodia. Cell Motil Cytoskeleton 48:109-20
Totsukawa, G; Yamakita, Y; Yamashiro, S et al. (2000) Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J Cell Biol 150:797-806

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