Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37CA063585-14
Application #
7082216
Study Section
Special Emphasis Panel (NSS)
Program Officer
Thurin, Magdalena
Project Start
1994-05-01
Project End
2009-05-31
Budget Start
2006-06-01
Budget End
2007-05-31
Support Year
14
Fiscal Year
2006
Total Cost
$806,129
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
020520466
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Alonso, Sergio; Dai, Yuichi; Yamashita, Kentaro et al. (2015) Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans. Oncotarget 6:3420-31
Kamiyama, H; Suzuki, K; Maeda, T et al. (2012) DNA demethylation in normal colon tissue predicts predisposition to multiple cancers. Oncogene 31:5029-37
Samuelsson, Johanna; Alonso, Sergio; Ruiz-Larroya, Tatiana et al. (2011) Frequent somatic demethylation of RAPGEF1/C3G intronic sequences in gastrointestinal and gynecological cancer. Int J Oncol 38:1575-7
Samuelsson, Johanna K; Alonso, Sergio; Yamamoto, Fumiichiro et al. (2010) DNA fingerprinting techniques for the analysis of genetic and epigenetic alterations in colorectal cancer. Mutat Res 693:61-76
Bilbao, Cristina; Lara, Pedro Carlos; Ramirez, Raquel et al. (2010) Microsatellite instability predicts clinical outcome in radiation-treated endometrioid endometrial cancer. Int J Radiat Oncol Biol Phys 76:9-13
Baranovskaya, Svetlana; Martin, Yolanda; Alonso, Sergio et al. (2009) Down-regulation of epidermal growth factor receptor by selective expansion of a 5'-end regulatory dinucleotide repeat in colon cancer with microsatellite instability. Clin Cancer Res 15:4531-7
Zhou, Wenyun; Alonso, Sergio; Takai, Daisaku et al. (2008) Requirement of RIZ1 for cancer prevention by methyl-balanced diet. PLoS One 3:e3390
Davalos, V; Dopeso, H; Velho, S et al. (2007) High EPHB2 mutation rate in gastric but not endometrial tumors with microsatellite instability. Oncogene 26:308-11
Gonzalez-Garcia, Isabel; Castells, Antoni (2007) New insights into a controversial topic: the methylation-cancer connection. Gastroenterology 132:2069-70;discussion 2070-1
Bilbao, Cristina; Rodriguez, German; Ramirez, Raquel et al. (2006) The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer. Int J Cancer 119:563-70

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